Phytessence™ Holyherb - A Holistic Solution to Protecting our DNA!
Consumers today continue to look for more traditional and “natural” products that improve and support healthy skin. Aloe vera and linden flowers for after suncare, willowbark for acne treatment, and milk for skin conditioning are just a few examples of what our customers are promoting. DNA, or deoxyribonucleic acid, plays a fundamental role in cellular function and is the blueprint for future cell construction. DNA is very fragile and can be easily damaged by environmental attacks, in particular UVB damage.
Phytessence Holyherb is a botanical extract proven to help protect and repair cells. Holyherb is primarily composed of homoeriodictyol and eriodictyol, flavonoid actives that help to protect the plant from the harmful rays of the sun. Testing was performed on Phytessence Holyherb’s ability to protect and repair cells by evaluating DNA fragmentation by cell death detection elisa (CDDE) and the expression of P53 protein, a stress marker produced when cells are damaged, via fluorescence iconography.
As the activity of Phytessence Holyherb increased from 0.03% to 0.7%, DNA fragmentation decreased 23% to 52%, respectively. This data shows that cells treated with Phytessence Holyherb are shielded from UVB damage and, as a result, help to maintain healthy, beautiful skin.
Protein p53 is regarded as the “guardian of the genome” because it is activated when DNA is damaged for rapid DNA repair. Well repaired cells become viable and help to rejuvenate the skin by providing the energy necessary for regeneration. Utilizing fluorescence iconography, epidermal keratinocytes were incubated with Phytessence Holyherb and irradiated with UVB to analyze how active protein p53 is.
A muted green image indicates no activation of protein p53 and a bright, neon green image indicates a high concentration of protein p53. The results from fluorescence iconography show as the concentration of Phytessence Holyherb increases, the lower the concentration of protein p53. A lower concentration of protein p53 equates to less DNA damage and, consequently, healthier cells and skin.
